Some time after the Mousekewitz's have settled in America, they find that they are still having problems with the threat of cats. That makes them eager to try another home out in the west, where they are promised that mice and cats live in peace. Unfortunately, the one making this claim is an oily con artist named Cat R. Waul who is intent on his own sinister plan. Unaware of this, the Mousekewitz's begin their journey west, while their true cat friend, Tiger, follows intent on following his girlfriend gone in the same direction.
A girl, a dog and her best pal set out to save a mountain from a gold-hungry corporation. But the key lies closer to home, with her sidekick pup, Xico.
A homesick alien crash-lands his spaceship near the colorful African Jungle. His new animal friends need to get him back to his ship and teach him about friendship and fun before his Space-Conqueror father can take over the planet.